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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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D-α-Tocopherol acetate can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine. This product is for research use only and not sold to patients.
Can be hydrolyzed to d-alpha-tocopherol and absorbed in the small intestine.
Inhibits LPS-induced production of NO, prostaglandin E2, and pro-inflammatory cytokines.
Exhibits a slight suppression on the activation of NF-κB p50 and p65.
Appears as a liquid, colorless to light yellow.
Identified as an endogenous metabolite.
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Betaine-d9 (chloride) is the deuterium labeled Betaine chloride. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Vitamin A (all-trans-Retinol) is an endogenous metabolite for research applications. This solid compound typically appears off-white to yellow and is known for its cytotoxic and growth inhibitory activities against various cell lines, making it suitable for studies in cellular effects and metabolic pathways.
Endogenous metabolite
Used for research applications
Solid form, off-white to yellow color
Soluble in ethanol (100 mg/mL), requiring ultrasonic aid for dissolution
Exhibits cytotoxicity against human normal fibroblasts
Shows growth inhibitory activity against human cancer cell lines
Unstable in solutions; freshly prepared solutions are recommended
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Vitamin K5 hydrochloride is a photosensitizer and an antimicrobial agent. It is a specific PKM2 inhibitor and induces apoptosis of colon 26 cells. It can be utilized in research for infection and cancer, and as a preservative for pharmaceuticals, foods, and beverages.
Increases antibacterial effects of UVA irradiation on various bacteria
Generates superoxide anion radical and hydroxyl radical
Inhibits cellular glucose consumption and lactate production
Suppresses proliferation of colon 26 cells
Induces cell apoptosis and increases caspase-3 activity in colon 26 cells
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Genipin 1-β-D-gentiobioside is an abundant and bioactive iridoid glycoside found in Gardenia jasminoides Ellis. It exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities. This product is for research use only.
Abundant and bioactive iridoid glycoside
Exhibits hepatoprotective activity
Exhibits anti-inflammatory activity
Exhibits antioxidant activity
Exhibits antithrombotic activity
Suitable for research use
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Abscisic acid is an orally active plant hormone also present in animals. This white to off-white solid contributes to the regulation of glycemia in mammals. It has a molecular weight of 264.32 and a chemical formula of C15H20O4.
High purity of 99.88%
Acts as an orally active plant hormone
Contributes to glycemia regulation in mammals
Increases CTLA-4 expressing cells and enhances CTLA-4 MFI on CD4+ T cells expressing PPAR γ in vitro
Reduces disease activity and colonic inflammation in vivo mouse models
Improves colon histopathology and suppresses adhesion molecules
Store powder at -20°C for 3 years or 4°C for 2 years
Store in solvent at -80°C for 6 months or -20°C for 1 month
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Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. It inhibits adipocyte differentiation and promotes skin wound healing. This product can be used in the research of gastrointestinal ulceration.
Orally active anti-ulcer agent
Antioxidant activity
Inhibits adipocyte differentiation
Promotes skin wound healing
Useful in gastrointestinal ulceration research
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Resiniferatoxin is a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It can be isolated from the Euphorbia resinifera plant. It eliminates TRPV1+ primary sensory afferents and blunts cardiac sympathetic afferent reflex for a relatively long period. It is for research use only.
Selective agonist for the transient receptor potential vanilloid 1 (TRPV1) receptor.
Can be isolated from the Euphorbia resinifera plant.
Eliminates TRPV1+ primary sensory afferents.
Blunts cardiac sympathetic afferent reflex for a relatively long period.
Causes prolonged channel opening and calcium influx, leading to cytotoxicity in TRPV1-positive pain fibers or cell bodies.
For research use only.
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Aphidicolin is an inhibitor of DNA polymerase α and δ, preventing mitotic cell division by interfering with DNA polymerase activity. It is an antibiotic produced by the mold *Cephalosporium aphidicola*, inhibiting cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin also exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
Inhibits DNA polymerase α and δ
Prevents mitotic cell division
Interferes with DNA polymerase activity
Antibiotic produced by *Cephalosporium aphidicola*
Inhibits cellular deoxyribonucleic acid synthesis
Inhibits growth of herpes simplex virus
Exhibits anti-orthopoxvirus activity
Potentiates apoptosis induced by arabinosyl nucleosides
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-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model -Tocopherol phosphate disodium exhibits angiogenesis-promoting activity[1][2]
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